How much do we really know about the patron saint of immigrants? This fictionalized biopic fills in many of the details as it tells her compelling tale. Arriving in New York City in 1889 to help the thousands of Italian immigrants already in the city, Francesca Cabrini, in poor health herself, is greeted by disease, crime and impoverished children. With broken English, she soon sets off to convince New York's mayor to secure housing and healthcare for society's most vulnerable, building a revolutionary healthcare system that eventually included 67 institutions, from schools, camps and orphanages to hospitals, shelters and chapels.